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-Structure paper
Title | Structural basis of human CYP51 inhibition by antifungal azoles. |
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Journal, issue, pages | J. Mol. Biol., Vol. 397, Page 1067-1078, Year 2010 |
Publish date | Sep 15, 2009 (structure data deposition date) |
![]() | Strushkevich, N. / Usanov, S.A. / Park, H.W. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.8 - 3.12 Å |
Structure data | ![]() PDB-3jus: ![]() PDB-3juv: ![]() PDB-3ld6: |
Chemicals | ![]() ChemComp-ECL: ![]() ChemComp-HEM: ![]() ChemComp-ECN: ![]() ChemComp-HOH: ![]() ChemComp-KKK: |
Source |
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![]() | OXIDOREDUCTASE / cytochrome P450 / sterol 14alpha-demethylase / econazole / Structural Genomics / Structural Genomics Consortium / SGC / Cholesterol biosynthesis / Endoplasmic reticulum / Heme / Iron / Lipid synthesis / Membrane / Metal-binding / Microsome / Monooxygenase / NADP / Steroid biosynthesis / Sterol biosynthesis / Transmembrane / Alternative splicing / Polymorphism / ketoconazole |