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Structure paper

TitleStructural basis for the cooperative interplay between the two causative gene products of combined factor V and factor VIII deficiency.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 107, Page 4034-4039, Year 2010
Publish dateJul 17, 2009 (structure data deposition date)
AuthorsNishio, M. / Kamiya, Y. / Mizushima, T. / Wakatsuki, S. / Sasakawa, H. / Yamamoto, K. / Uchiyama, S. / Noda, M. / McKay, A.R. / Fukui, K. ...Nishio, M. / Kamiya, Y. / Mizushima, T. / Wakatsuki, S. / Sasakawa, H. / Yamamoto, K. / Uchiyama, S. / Noda, M. / McKay, A.R. / Fukui, K. / Hauri, H.P. / Kato, K.
External linksProc. Natl. Acad. Sci. USA / PubMed:20142513
MethodsX-ray diffraction
Resolution1.84 Å
Structure data

PDB-3a4u:
Crystal structure of MCFD2 in complex with carbohydrate recognition domain of ERGIC-53
Method: X-RAY DIFFRACTION / Resolution: 1.84 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN TRANSPORT / LECTIN / ERGIC / ER / GOLGI / TRANSPORT / Disulfide bond / Endoplasmic reticulum / ER-Golgi transport / Golgi apparatus / Membrane / Transmembrane / Disease mutation

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