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TitleStructural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 140, Page 246-256, Year 2010
Publish dateDec 4, 2009 (structure data deposition date)
AuthorsYu, B. / Martins, I.R. / Li, P. / Amarasinghe, G.K. / Umetani, J. / Fernandez-Zapico, M.E. / Billadeau, D.D. / Machius, M. / Tomchick, D.R. / Rosen, M.K.
External linksCell(Cambridge,Mass. ) / PubMed:20141838
MethodsX-ray diffraction
Resolution2.731 Å
Structure data

PDB-3ky9:
Autoinhibited Vav1
Method: X-RAY DIFFRACTION / Resolution: 2.731 Å

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsAPOPTOSIS / VAV1 / CALPONIN HOMOLOGY DOMAIN / DBL HOMOLOGY DOMAIN / PLECKSTRIN HOMOLOGY DOMAIN / C1 DOMAIN / Guanine-nucleotide releasing factor / Metal-binding / Phosphoprotein / Proto-oncogene / SH2 domain / SH3 domain / Zinc-finger

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