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Structure paper

TitleSolution structure of the regulatory domain of human cardiac troponin C in complex with the switch region of cardiac troponin I and W7: the basis of W7 as an inhibitor of cardiac muscle contraction.
Journal, issue, pagesJ. MOL. CELL. CARDIOL., Vol. 48, Page 925-933, Year 2010
Publish dateDec 16, 2009 (structure data deposition date)
AuthorsOleszczuk, M. / Robertson, I.M. / Li, M.X. / Sykes, B.D.
External linksJ. MOL. CELL. CARDIOL. / PubMed:20116385
MethodsNMR (solution)
Structure data

PDB-2krd:
Solution Structure of the Regulatory Domain of Human Cardiac Troponin C in Complex with the Switch Region of cardiac Troponin I and W7
Method: SOLUTION NMR

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-WW7:
N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / cardiac troponin C / regulatory domain / troponin I / switch region / W7 / Acetylation / Calcium / Cardiomyopathy / Disease mutation / Muscle protein / Polymorphism / Actin-binding / Phosphoprotein

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