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TitleCrystal Structure of Escherichia coli Enterobactin-specific Isochorismate Synthase (EntC) Bound to its Reaction Product Isochorismate: Implications for the Enzyme Mechanism and Differential Activity of Chorismate-utilizing Enzymes
Journal, issue, pagesJ. Mol. Biol., Vol. 397, Page 290-300, Year 2010
Publish dateJun 18, 2009 (structure data deposition date)
AuthorsSridharan, S. / Howard, N. / Kerbarh, O. / Blaszczyk, M. / Abell, C. / Blundell, T.L.
External linksJ. Mol. Biol. / PubMed:20079748
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-3hwo:
Crystal structure of Escherichia coli enterobactin-specific isochorismate synthase EntC in complex with isochorismate
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ISC:
(5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsISOMERASE / isochorismate synthase / EntC / chorismate-utilizing enzymes / siderophore / enterobactin / Enterobactin biosynthesis / Ion transport / Iron / Iron transport / Transport

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