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| Title | Structure of HIV-1 reverse transcriptase with the inhibitor beta-Thujaplicinol bound at the RNase H active site. |
|---|---|
| Journal, issue, pages | Structure, Vol. 17, Page 1625-1635, Year 2009 |
| Publish date | Jul 27, 2009 (structure data deposition date) |
Authors | Himmel, D.M. / Maegley, K.A. / Pauly, T.A. / Bauman, J.D. / Das, K. / Dharia, C. / Clark, A.D. / Ryan, K. / Hickey, M.J. / Love, R.A. ...Himmel, D.M. / Maegley, K.A. / Pauly, T.A. / Bauman, J.D. / Das, K. / Dharia, C. / Clark, A.D. / Ryan, K. / Hickey, M.J. / Love, R.A. / Hughes, S.H. / Bergqvist, S. / Arnold, E. |
External links | Structure / PubMed:20004166 |
| Methods | X-ray diffraction |
| Resolution | 2.04 - 2.8 Å |
| Structure data | ![]() PDB-3ig1: ![]() PDB-3k2p: |
| Chemicals | ![]() ChemComp-JTH: ![]() ChemComp-MN: ![]() ChemComp-HOH: |
| Source |
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Keywords | TRANSFERASE / RNASE H INHIBITOR / PROTEIN-INHIBITOR COMPLEX / STRUCTURE-BASED DRUG DESIGN / TROPOLONES / TROPYLIUM ION / DIVALENT CATION CHELATOR / AIDS / DNA-DIRECTED DNA POLYMERASE / METAL-BINDING / MULTIFUNCTIONAL ENZYME / NUCLEOTIDYLTRANSFERASE / RNA-BINDING / RNA-DIRECTED DNA POLYMERASE / HYDROLASE / reverse transcriptase / HIV |
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human immunodeficiency virus type 1 bh10
human immunodeficiency virus type 1
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