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Structure paper

TitleCrystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism.
Journal, issue, pagesJ. Mol. Biol., Vol. 396, Page 441-451, Year 2010
Publish dateOct 16, 2009 (structure data deposition date)
AuthorsAnnalora, A.J. / Goodin, D.B. / Hong, W.X. / Zhang, Q. / Johnson, E.F. / Stout, C.D.
External linksJ. Mol. Biol. / PubMed:19961857
MethodsX-ray diffraction
Resolution2.5 - 2.8 Å
Structure data

PDB-3k9v:
Crystal structure of rat mitochondrial P450 24A1 S57D in complex with CHAPS
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3k9y:
Crystal structure of rat mitochondrial P450 24A1 S57D in complex with CYMAL-5
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-CPS:
3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE / detergent*YM

ChemComp-HOH:
WATER

ChemComp-CM5:
5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE / detergent*YM

Source
  • rattus norvegicus (Norway rat)
KeywordsOXIDOREDUCTASE / MITOCHONDRIAL CYTOCHROME P450 / MONOTOPIC MEMBRANE PROTEIN / MONOOXYGENASE / VITAMIN D HORMONE METABOLISM / ADRENODOXIN

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