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TitleCrystal structure and molecular dynamics studies of human purine nucleoside phosphorylase complexed with 7-deazaguanine.
Journal, issue, pagesJ. Struct. Biol., Vol. 169, Page 379-388, Year 2010
Publish dateAug 13, 2009 (structure data deposition date)
AuthorsCaceres, R.A. / Timmers, L.F. / Pauli, I. / Gava, L.M. / Ducati, R.G. / Basso, L.A. / Santos, D.S. / de Azevedo, W.F.
External linksJ. Struct. Biol. / PubMed:19932753
MethodsX-ray diffraction
Resolution2.75 Å
Structure data

PDB-3iny:
Crystal structure of human purine nucleoside phosphorylase in complex with 7-deazaguanine
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-7DG:
7-DEAZAGUANINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / 7-deazaguanine / Cytoskeleton / Disease mutation / Glycosyltransferase

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