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TitleCrystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations.
Journal, issue, pagesStructure, Vol. 17, Page 1505-1514, Year 2009
Publish dateAug 6, 2009 (structure data deposition date)
AuthorsLobo, P.A. / Van Petegem, F.
External linksStructure / PubMed:19913485
MethodsX-ray diffraction
Resolution1.7 - 2.9 Å
Structure data

PDB-3ila:
Crystal structure of rabbit ryanodine receptor 1 N-terminal domain (9-205)
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-3im5:
Crystal structure of mouse Ryanodine Receptor 2 (residues 1-217)
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

PDB-3im6:
Crystal structure of mouse Ryanodine Receptor 2 mutant V186M
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-3im7:
Crystal structure of mouse Ryanodine Receptor 2 N-terminal domain (1-217) disease mutant A77V
Method: X-RAY DIFFRACTION / Resolution: 2.21 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • oryctolagus cuniculus (rabbit)
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN / BETA TREFOIL / Calcium channel / Calcium transport / Glycoprotein / Ion transport / Ionic channel / Membrane / Phosphoprotein / Receptor / S-nitrosylation / Transmembrane / Transport / ryanodine receptor 2 / calcium release channel / cardiac channel / ion channel / ARVC2 / ARVD2 / CPVT / cardiac arrhythmia / arrhythmia / disease mutation / Ryanodine receptor / tachycardia

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