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TitleStructural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations.
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 139, Page 312-324, Year 2009
Publish dateAug 6, 2009 (structure data deposition date)
AuthorsLee, Y.S. / Kennedy, W.D. / Yin, Y.W.
External linksCell(Cambridge,Mass. ) / PubMed:19837034
MethodsX-ray diffraction
Resolution3.1 - 3.24 Å
Structure data

PDB-3ikl:
Crystal structure of Pol gB delta-I4.
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-3ikm:
Crystal structure of human mitochondrial DNA polymerase holoenzyme
Method: X-RAY DIFFRACTION / Resolution: 3.24 Å

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Human mitochondrial DNA polymerase / Disease mutation / DNA replication / DNA-binding / DNA-directed DNA polymerase / Magnesium / Mitochondrion / Neuropathy / Nucleotidyltransferase / Progressive external ophthalmoplegia / Transit peptide

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