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-Structure paper
Title | Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 106, Page 18345-18350, Year 2009 |
Publish date | May 18, 2009 (structure data deposition date) |
Authors | Zhang, H. / Liu, J.H. / Yang, W. / Springer, T. / Shimaoka, M. / Wang, J.H. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:19805116 |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.5 Å |
Structure data | PDB-3hi5: PDB-3hi6: |
Chemicals | ChemComp-HOH: ChemComp-MN: ChemComp-SO4: |
Source |
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Keywords | IMMUNE SYSTEM / Fab fragment / ligand mimetic / integrin / I domain / cell adhesion / cell adhesion/immune system / Fab / ligand mimetic antibody / Alternative splicing / Calcium / Disulfide bond / Glycoprotein / Magnesium / Membrane / Polymorphism / Receptor / Transmembrane / cell adhesion-immune system COMPLEX |