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Structure paper

TitleStructural snapshots of heparin depolymerization by heparin lyase I.
Journal, issue, pagesJ. Biol. Chem., Vol. 284, Page 34019-34027, Year 2009
Publish dateAug 6, 2009 (structure data deposition date)
AuthorsHan, Y.H. / Garron, M.L. / Kim, H.Y. / Kim, W.S. / Zhang, Z. / Ryu, K.S. / Shaya, D. / Xiao, Z. / Cheong, C. / Kim, Y.S. ...Han, Y.H. / Garron, M.L. / Kim, H.Y. / Kim, W.S. / Zhang, Z. / Ryu, K.S. / Shaya, D. / Xiao, Z. / Cheong, C. / Kim, Y.S. / Linhardt, R.J. / Jeon, Y.H. / Cygler, M.
External linksJ. Biol. Chem. / PubMed:19801541
MethodsX-ray diffraction
Resolution1.3 - 2 Å
Structure data

PDB-3ikw:
Structure of Heparinase I from Bacteroides thetaiotaomicron
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-3ilr:
Structure of Heparinase I from Bacteroides thetaiotaomicron in complex with tetrasaccharide product
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-3imn:
Crystal structure of heparin lyase I from Bacteroides thetaiotaomicron
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

PDB-3in9:
Crystal structure of heparin lyase I complexed with disaccharide heparin
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3ina:
Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • bacteroides thetaiotaomicron (bacteria)
KeywordsLYASE / Heparin / polysaccharide lyase / beta-jelly roll / jelly roll

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