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TitleStructure and activation mechanism of the CHK2 DNA damage checkpoint kinase.
Journal, issue, pagesMol. Cell, Vol. 35, Page 818-829, Year 2009
Publish dateJul 7, 2009 (structure data deposition date)
AuthorsCai, Z. / Chehab, N.H. / Pavletich, N.P.
External linksMol. Cell / PubMed:19782031
MethodsX-ray diffraction
Resolution3 - 3.25 Å
Structure data

PDB-3i6u:
Structure and Activation Mechanism of the CHK2 DNA-Damage Checkpoint Kinase
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-3i6w:
Structure and Activation Mechanism of the CHK2 DNA-Damage Checkpoint Kinase
Method: X-RAY DIFFRACTION / Resolution: 3.25 Å

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Ser/Thr protein kinase / FHA domain / ATP-binding / Cell cycle / Disease mutation / Kinase / Li-Fraumeni syndrome / Magnesium / Metal-binding / Nucleotide-binding / Nucleus / Phosphoprotein / Proto-oncogene / Serine/threonine-protein kinase

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