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| Title | Resistance mechanism revealed by crystal structures of unliganded nelfinavir-resistant HIV-1 protease non-active site mutants N88D and N88S. |
|---|---|
| Journal, issue, pages | Biochem. Biophys. Res. Commun., Vol. 389, Page 295-300, Year 2009 |
| Publish date | Nov 24, 2009 (structure data deposition date) |
Authors | Bihani, S.C. / Das, A. / Prashar, V. / Ferrer, J.L. / Hosur, M.V. |
External links | Biochem. Biophys. Res. Commun. / PubMed:19720046 |
| Methods | X-ray diffraction |
| Resolution | 1.651 - 1.801 Å |
| Structure data | ![]() PDB-3kt2: ![]() PDB-3kt5: |
| Chemicals | ![]() ChemComp-HOH: |
| Source |
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Keywords | HYDROLASE / Drug Resistant Mutation / N88D / Nelfinavir / HIV-1 protease / Protease / Drug Resistant / Mutation / N88S |
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human immunodeficiency virus type 1
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