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Structure paper

TitleStructural evidence for a sequential release mechanism for activation of heterotrimeric g proteins.
Journal, issue, pagesJ. Mol. Biol., Vol. 393, Page 882-897, Year 2009
Publish dateDec 2, 2008 (structure data deposition date)
AuthorsKapoor, N. / Menon, S.T. / Chauhan, R. / Sachdev, P. / Sakmar, T.P.
External linksJ. Mol. Biol. / PubMed:19703466
MethodsX-ray diffraction
Resolution2.3 - 2.57 Å
Structure data

PDB-3ffa:
Crystal Structure of a fast activating G protein mutant
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3ffb:
Gi-alpha-1 mutant in GDP bound form
Method: X-RAY DIFFRACTION / Resolution: 2.57 Å

Chemicals

ChemComp-GSP:
5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

Source
  • rattus norvegicus (Norway rat)
KeywordsSIGNALING PROTEIN / Gi-alpha-1 mutant protein GTP-gamma-S bound / GTP-binding / Lipoprotein / Myristate / Nucleotide-binding / Palmitate / Transducer / SIGNAL TRANSDUCTION / Gi-alpha-1 fast activating mutant

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