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Structure paper

TitleReplication across template T/U by human DNA polymerase-iota.
Journal, issue, pagesStructure, Vol. 17, Page 974-980, Year 2009
Publish dateApr 17, 2009 (structure data deposition date)
AuthorsJain, R. / Nair, D.T. / Johnson, R.E. / Prakash, L. / Prakash, S. / Aggarwal, A.K.
External linksStructure / PubMed:19604477
MethodsX-ray diffraction
Resolution2.2 - 2.85 Å
Structure data

PDB-3h40:
Binary complex of human DNA polymerase iota with template U/T
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3h4b:
Ternary complex of human DNA polymerase iota with template U/T and incoming dATP
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-3h4d:
Ternary complex of human DNA polymerase iota with template U/T and incoming dGTP
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-DTP:
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-DGT:
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

Source
  • homo sapiens (human)
KeywordsREPLICATION/DNA / DNA polymerase iota / replication / DNA damage / DNA repair / DNA replication / DNA synthesis / DNA-binding / DNA-directed DNA polymerase / Magnesium / Metal-binding / Mutator protein / Nucleotidyltransferase / Nucleus / Schiff base / Transferase / REPLICATION-DNA COMPLEX

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