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-Structure paper
Title | X-ray crystal structure of human heme oxygenase-1 with (2R,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-4[((5-trifluoromethylpyridin-2-yl)thio)methyl]-1,3-dioxolane: a novel, inducible binding mode. |
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Journal, issue, pages | J. Med. Chem., Vol. 52, Page 4946-4950, Year 2009 |
Publish date | Jun 2, 2009 (structure data deposition date) |
![]() | Rahman, M.N. / Vlahakis, J.Z. / Vukomanovic, D. / Szarek, W.A. / Nakatsu, K. / Jia, Z. |
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Methods | X-ray diffraction |
Resolution | 2.19 Å |
Structure data | ![]() PDB-3hok: |
Chemicals | ![]() ChemComp-HEM: ![]() ChemComp-Q80: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / protein-inhibitor complex / alpha helices / Endoplasmic reticulum / Heme / Iron / Metal-binding / Microsome / Phosphoprotein / Polymorphism |