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TitleDifferential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors
Journal, issue, pagesImmunity, Vol. 31, Page 47-59, Year 2009
Publish dateMay 7, 2009 (structure data deposition date)
AuthorsPellicci, D.G. / Patel, O. / Kjer-Nielsen, L. / Pang, S.S. / Sullivan, L.C. / Kyparissoudis, K. / Brooks, A.G. / Reid, H.H. / Gras, S. / Lucet, I.S. ...Pellicci, D.G. / Patel, O. / Kjer-Nielsen, L. / Pang, S.S. / Sullivan, L.C. / Kyparissoudis, K. / Brooks, A.G. / Reid, H.H. / Gras, S. / Lucet, I.S. / Koh, R. / Smyth, M.J. / Mallevaey, T. / Matsuda, J.L. / Gapin, L. / McCluskey, J. / Godfrey, D.I. / Rossjohn, J.
External linksImmunity / PubMed:19592275
MethodsX-ray diffraction
Resolution2.5 - 2.9 Å
Structure data

PDB-3he6:
Crystal structure of mouse CD1d-alpha-galactosylceramide with mouse Valpha14-Vbeta8.2 NKT TCR
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-3he7:
Crystal structure of mouse CD1d-alpha-galactosylceramide with mouse Valpha14-Vbeta7 NKT TCR
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3huj:
Crystal structure of human CD1d-alpha-Galactosylceramide in complex with semi-invariant NKT cell receptor
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-AGH:
N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / mouse CD1d / mouse NKT T-cell receptors / Cell membrane / Disulfide bond / Endosome / Glycoprotein / Immune response / Immunoglobulin domain / Innate immunity / Lysosome / Membrane / Transmembrane / MHC I / CD1d / NKT T cell receptor / alpha-galactosylceramide / protein receptor complex / Host-virus interaction / Disease mutation / Glycation / Pyrrolidone carboxylic acid / Secreted

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