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TitleAllosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78.
Journal, issue, pagesMol. Cell, Vol. 34, Page 674-685, Year 2009
Publish dateApr 29, 2009 (structure data deposition date)
AuthorsDas, R. / Mariano, J. / Tsai, Y.C. / Kalathur, R.C. / Kostova, Z. / Li, J. / Tarasov, S.G. / McFeeters, R.L. / Altieri, A.S. / Ji, X. ...Das, R. / Mariano, J. / Tsai, Y.C. / Kalathur, R.C. / Kostova, Z. / Li, J. / Tarasov, S.G. / McFeeters, R.L. / Altieri, A.S. / Ji, X. / Byrd, R.A. / Weissman, A.M.
External linksMol. Cell / PubMed:19560420
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-3h8k:
Crystal structure of Ube2g2 complxed with the G2BR domain of gp78 at 1.8-A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / alpha beta / all alpha / Ubl conjugation pathway / Endoplasmic reticulum / Membrane / Metal-binding / Phosphoprotein / Receptor / Transmembrane / Zinc-finger

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