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TitleStructure of Insoluble Rat Sperm Glyceraldehyde-3-Phosphate Dehydrogenase (Gapdh) Via Heterotetramer Formation with Escherichia Coli Gapdh Reveals Target for Contraceptive Design.
Journal, issue, pagesJ. Biol. Chem., Vol. 284, Page 22703-, Year 2009
Publish dateJul 25, 2008 (structure data deposition date)
AuthorsFrayne, J. / Taylor, A. / Cameron, G. / Hadfield, A.T.
External linksJ. Biol. Chem. / PubMed:19542219
MethodsX-ray diffraction
Resolution2.2 - 2.38 Å
Structure data

PDB-2vyn:
Structure of E.Coli GAPDH Rat Sperm GAPDH heterotetramer
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-2vyv:
Structure of E.Coli GAPDH Rat Sperm GAPDH heterotetramer
Method: X-RAY DIFFRACTION / Resolution: 2.38 Å

Chemicals

ChemComp-FMT:
FORMIC ACID

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-HOH:
WATER

ChemComp-1GP:
SN-GLYCEROL-1-PHOSPHATE

Source
  • escherichia coli bl21(de3) (bacteria)
  • rattus norvegicus (Norway rat)
KeywordsOXIDOREDUCTASE / GAPDH / CONTRACEPTIVE / RAT SPERM / GLYCERALDEHYDE-3-PHOSPHATE / ALPHA CHLOROHYDRIN / NAD / CYTOPLASM / GLYCOLYSIS

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