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| Title | The crystal structures of substrate and nucleotide complexes of Enterococcus faecium aminoglycoside-2''-phosphotransferase-IIa [APH(2'')-IIa] provide insights into substrate selectivity in the APH(2'') subfamily. |
|---|---|
| Journal, issue, pages | J. Bacteriol., Vol. 191, Page 4133-4143, Year 2009 |
| Publish date | May 2, 2009 (structure data deposition date) |
Authors | Young, P.G. / Walanj, R. / Lakshmi, V. / Byrnes, L.J. / Metcalf, P. / Baker, E.N. / Vakulenko, S.B. / Smith, C.A. |
External links | J. Bacteriol. / PubMed:19429619 |
| Methods | X-ray diffraction |
| Resolution | 2.45 - 2.5 Å |
| Structure data | ![]() PDB-3ham: ![]() PDB-3hav: |
| Chemicals | ![]() ChemComp-LLL: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-ATP: ![]() ChemComp-MG: ![]() ChemComp-SRY: |
| Source |
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Keywords | TRANSFERASE / aminoglycoside / gentamicin / antibiotic resistance / streptomycin |
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enterococcus faecium (bacteria)
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