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-Structure paper
Title | Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity. |
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Journal, issue, pages | Antimicrob. Agents Chemother., Vol. 53, Page 3065-3073, Year 2009 |
Publish date | Dec 18, 2008 (structure data deposition date) |
![]() | Bourne, C.R. / Bunce, R.A. / Bourne, P.C. / Berlin, K.D. / Barrow, E.W. / Barrow, W.W. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.2881 - 2.4 Å |
Structure data | ![]() PDB-3fl8: ![]() PDB-3fl9: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-RAR: ![]() ChemComp-HOH: ![]() ChemComp-TOP: |
Source |
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![]() | OXIDOREDUCTASE / PYRIMIDINE / DIHYDROPHTHALAZINE |