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TitleOptimizing pH response of affinity between protein G and IgG Fc: how electrostatic modulations affect protein-protein interactions.
Journal, issue, pagesJ. Biol. Chem., Vol. 284, Page 12373-12383, Year 2009
Publish dateNov 26, 2008 (structure data deposition date)
AuthorsWatanabe, H. / Matsumaru, H. / Ooishi, A. / Feng, Y. / Odahara, T. / Suto, K. / Honda, S.
External linksJ. Biol. Chem. / PubMed:19269963
MethodsX-ray diffraction
Resolution1.4 - 1.6 Å
Structure data

PDB-2zw0:
Crystal structure of a Streptococcal protein G B1 mutant
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-2zw1:
Crystal structure of a Streptococcal protein G B1 mutant
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • finegoldia magna (bacteria)
KeywordsIMMUNE SYSTEM / IMMUNOGLOBULIN BINDING DOMAIN / PH-DEPENDENT LIGAND BINDING

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