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-Structure paper
Title | Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 106, Page 450-455, Year 2009 |
Publish date | Oct 28, 2008 (structure data deposition date) |
![]() | Scheuermann, T.H. / Tomchick, D.R. / Machius, M. / Guo, Y. / Bruick, R.K. / Gardner, K.H. |
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Methods | X-ray diffraction |
Resolution | 1.17 - 1.598 Å |
Structure data | ![]() PDB-3f1n: ![]() PDB-3f1o: ![]() PDB-3f1p: |
Chemicals | ![]() ChemComp-EDO: ![]() ChemComp-HOH: ![]() ChemComp-2XY: |
Source |
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![]() | TRANSCRIPTION / PAS domain / heterodimer / internal cavity / Activator / Angiogenesis / Congenital erythrocytosis / Developmental protein / Differentiation / Disease mutation / DNA-binding / Hydroxylation / Nucleus / Phosphoprotein / Transcription regulation / Ubl conjugation / Alternative splicing / Polymorphism |