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TitleA Structural Model of the Staphylococcus Aureus Clfa-Fibrinogen Interaction Opens New Avenues for the Design of Anti-Staphylococcal Therapeutics.
Journal, issue, pagesPlos Pathog., Vol. 4, Page 226-, Year 2008
Publish dateMar 25, 2008 (structure data deposition date)
AuthorsGanesh, V.K. / Rivera, J.J. / Smeds, E. / Ko, Y.P. / Bowden, M.G. / Wann, E.R. / Gurusiddappa, S. / Fitzgerald, J.R. / Hook, M.
External linksPlos Pathog. / PubMed:19043557
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-2vr3:
Structural and Biochemical Characterization of Fibrinogen binding to ClfA from Staphylocccus aureus
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • staphylococcus aureus (bacteria)
  • homo sapiens (human)
KeywordsCELL ADHESION / PLATELET AGGREGATION / PEPTIDOGLYCAN-ANCHOR / STAPHYLOCOCCUS AUREUS / FIBRINOGEN GAMMA-CHAIN / SECRETED / CELL WALL / VIRULENCE / CLUMPING FACTOR

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