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-Structure paper
Title | General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold. |
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Journal, issue, pages | J. Biol. Chem., Year 2008 |
Publish date | Jul 23, 2008 (structure data deposition date) |
Authors | Vincke, C. / Loris, R. / Saerens, D. / Martinez-Rodriguez, S. / Muyldermans, S. / Conrath, K. |
External links | J. Biol. Chem. / PubMed:19010777 |
Methods | X-ray diffraction |
Resolution | 1.85 - 2.9 Å |
Structure data | PDB-3dwt: PDB-3eak: PDB-3eba: |
Chemicals | ChemComp-GOL: ChemComp-HOH: ChemComp-SO4: |
Source |
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Keywords | IMMUNE SYSTEM / nanobody / humanization / antibody / dromedary VH domain / VHH domain / IMMUNE SYSTEM/HYDROLASE / ANTIGEN-ANTIBODY COMPLEX / IMMUNOGLOBULIN / AMYLOID FIBRIL formation inhibition / Amyloid / Antimicrobial / Bacteriolytic enzyme / Disease mutation / Glycosidase / Hydrolase / Polymorphism / IMMUNE SYSTEM-HYDROLASE COMPLEX |