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Structure paper

TitleThe oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 105, Page 13339-13344, Year 2008
Publish dateJun 27, 2008 (structure data deposition date)
AuthorsWilson, D.N. / Schluenzen, F. / Harms, J.M. / Starosta, A.L. / Connell, S.R. / Fucini, P.
External linksProc. Natl. Acad. Sci. Usa / PubMed:18757750
MethodsX-ray diffraction
Resolution3.5 Å
Structure data

PDB-3dll:
The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ZLD:
N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide / antibiotic*YM

ChemComp-ZN:
Unknown entry

Source
  • deinococcus radiodurans (radioresistant)
KeywordsRIBOSOME / Antibiotic / oxazolidinone / Linezolid / Ribonucleoprotein / Ribosomal protein / RNA-binding / rRNA-binding / tRNA-binding / Methylation / Metal-binding / Zinc-finger

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