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Structure paper

TitleBiochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis.
Journal, issue, pagesChem. Biol., Vol. 15, Page 842-853, Year 2008
Publish dateMay 2, 2008 (structure data deposition date)
AuthorsZhang, C. / Bitto, E. / Goff, R.D. / Singh, S. / Bingman, C.A. / Griffith, B.R. / Albermann, C. / Phillips, G.N. / Thorson, J.S.
External linksChem. Biol. / PubMed:18721755
MethodsX-ray diffraction
Resolution1.9 - 2.79 Å
Structure data

PDB-3d0q:
Crystal structure of calG3 from Micromonospora echinospora determined in space group I222
Method: X-RAY DIFFRACTION / Resolution: 2.79 Å

PDB-3d0r:
Crystal structure of calG3 from Micromonospora echinospora determined in space group P2(1)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-MPO:
3[N-MORPHOLINO]PROPANE SULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

ChemComp-PE4:
2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL / precipitant*YM

Source
  • micromonospora echinospora (bacteria)
KeywordsTRANSFERASE / Calicheamicin synthesis / glycosyltransferase / enediyne antibiotic

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