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TitleStructural and Functional Analysis of the Crb2-Brct2 Domain Reveals Distinct Roles in Checkpoint Signaling and DNA Damage Repair.
Journal, issue, pagesGenes Dev., Vol. 22, Page 2034-, Year 2008
Publish dateJul 3, 2008 (structure data deposition date)
AuthorsKilkenny, M.L. / Dore, A. / Roe, S.M. / Nestoras, K. / Ho, J.C.Y. / Watts, F.Z. / Pearl, L.H.
External linksGenes Dev. / PubMed:18676809
MethodsX-ray diffraction
Resolution2.3 - 3.1 Å
Structure data

PDB-2vxb:
Structure of the Crb2-BRCT2 domain
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-2vxc:
Structure of the Crb2-BRCT2 domain complex with phosphopeptide.
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-PR:
PRASEODYMIUM ION

ChemComp-HOH:
WATER

Source
  • schizosaccharomyces pombe (fission yeast)
  • homo sapiens (human)
KeywordsCELL CYCLE / BRCT / NUCLEUS / DNA DAMAGE / DNA REPLICATION INHIBITOR / PHOSPHOPROTEIN / CHECKPOINT SIGNALLING

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