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TitleCrystal engineering of HIV-1 reverse transcriptase for structure-based drug design.
Journal, issue, pagesNucleic Acids Res., Vol. 36, Page 5083-5092, Year 2008
Publish dateJun 27, 2008 (structure data deposition date)
AuthorsBauman, J.D. / Das, K. / Ho, W.C. / Baweja, M. / Himmel, D.M. / Clark, A.D. / Oren, D.A. / Boyer, P.L. / Hughes, S.H. / Shatkin, A.J. / Arnold, E.
External linksNucleic Acids Res. / PubMed:18676450
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-3dlk:
Crystal Structure of an engineered form of the HIV-1 Reverse Transcriptase, RT69A
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus type 1 bh10
  • human immunodeficiency virus type 1
KeywordsTRANSFERASE / AIDS / HIV / REVERSE TRANSCRIPTASE / RT / crystal engineering / RNA-binding / RNA-directed DNA polymerase / Viral nucleoprotein

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