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Structure paper

TitleMechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity
Journal, issue, pagesJ. Biol. Chem., Vol. 283, Page 25863-25870, Year 2008
Publish dateSep 21, 2008 (structure data deposition date)
AuthorsBjelke, J.R. / Olsen, O.H. / Fodje, M. / Svensson, L.A. / Bang, S. / Bolt, G. / Kragelund, B.B. / Persson, E.
External linksJ. Biol. Chem. / PubMed:18640965
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-3ela:
Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-GLC:
alpha-D-glucopyranose

ChemComp-FUC:
alpha-L-fucopyranose

ChemComp-CA:
Unknown entry

ChemComp-0Z6:
D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-phenylalaninamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / Serine protease / BLOOD CLOTTING / HYDROLASE-HYDROLASE INHIBITOR complex

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