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-Structure paper
Title | The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore |
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Journal, issue, pages | J. Med. Chem., Vol. 51, Page 4653-4659, Year 2008 |
Publish date | Apr 9, 2008 (structure data deposition date) |
Authors | Xu, H. / Fairman, J.W. / Wijerathna, S.R. / Kreischer, N.R. / LaMacchia, J. / Helmbrecht, E. / Cooperman, B.S. / Dealwis, C. |
External links | J. Med. Chem. / PubMed:18610997 |
Methods | X-ray diffraction |
Resolution | 2.52 - 2.59 Å |
Structure data | PDB-2zlf: PDB-2zlg: |
Chemicals | ChemComp-HOH: ChemComp-MRT: ChemComp-GOL: |
Source |
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Keywords | OXIDOREDUCTASE / peptidomimetic inhibition eukaryotic ribonucleotide reductase / Allosteric enzyme / ATP-binding / Cytoplasm / DNA replication / Nucleotide-binding / Phosphoprotein |