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Structure paper

TitleThe S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release.
Journal, issue, pagesJ. Mol. Biol., Vol. 380, Page 244-, Year 2008
Publish dateOct 13, 2007 (structure data deposition date)
AuthorsZhou, A. / Wei, Z. / Stanley, P.L. / Read, R.J. / Stein, P.E. / Carrell, R.W.
External linksJ. Mol. Biol. / PubMed:18513745
MethodsX-ray diffraction
Resolution1.84 - 2.3 Å
Structure data

PDB-2vdx:
Crystal Structure of the reactive loop Cleaved Corticosteroid Binding Globulin
Method: X-RAY DIFFRACTION / Resolution: 1.84 Å

PDB-2vdy:
Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-HCY:
(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione / medication, hormone*YM

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / CORTISOL BINDING GLOBULIN / GLYCOPROTEIN / LIPID-BINDING / STEROID-BINDING / DISEASE MUTATION / CBG / SERPIN / CLEAVED / SECRETED / CORTISOL / CORTICOSTEROID BINDING GLOBULIN / TRANSPORT

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