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TitleCrystal Structures of the Mycobacterium Tuberculosis Secretory Antigen Alanine Dehydrogenase (Rv2780) in Apo and Ternary Complex Forms Captures "Open" and "Closed" Enzyme Conformations.
Journal, issue, pagesProteins, Vol. 72, Page 1089-, Year 2008
Publish dateFeb 17, 2008 (structure data deposition date)
AuthorsTripathi, S.M. / Ramachandran, R.
External linksProteins / PubMed:18491387
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-2voe:
Crystal structure of Rv2780 from M. tuberculosis H37Rv
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-2voj:
Ternary complex of M. tuberculosis Rv2780 with NAD and pyruvate
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-2OP:
(2S)-2-HYDROXYPROPANOIC ACID

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsOXIDOREDUCTASE / SECRETED / NAD / PYRUVATE

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