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Structure paper

TitleMutation of the Pdk1 Ph Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance.
Journal, issue, pagesMol. Cell. Biol., Vol. 28, Page 3258-, Year 2008
Publish dateDec 19, 2007 (structure data deposition date)
AuthorsBayascas, J.R. / Wullschleger, S. / Sakamoto, K. / Garcia-Martinez, J.M. / Clacher, C. / Komander, D. / Van Aalten, D.M.F. / Boini, K.M. / Lang, F. / Lipina, C. ...Bayascas, J.R. / Wullschleger, S. / Sakamoto, K. / Garcia-Martinez, J.M. / Clacher, C. / Komander, D. / Van Aalten, D.M.F. / Boini, K.M. / Lang, F. / Lipina, C. / Logie, L. / Sutherland, C. / Chudek, J.A. / Van Diepen, J.A. / Voshol, P.J. / Lucocq, J.M. / Alessi, D.R.
External linksMol. Cell. Biol. / PubMed:18347057
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-2vki:
Structure of the PDK1 PH domain K465E mutant
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / PLECKSTRIN HOMOLOGY / CANCER / DIABETES

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