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-Structure paper
Title | Effect of the Active Site D25N Mutation on the Structure, Stability, and Ligand Binding of the Mature HIV-1 Protease. |
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Journal, issue, pages | J. Biol. Chem., Vol. 283, Page 13459-13470, Year 2008 |
Publish date | Jan 5, 2008 (structure data deposition date) |
![]() | Sayer, J.M. / Liu, F. / Ishima, R. / Weber, I.T. / Louis, J.M. |
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Methods | X-ray diffraction |
Resolution | 1.05 - 1.3 Å |
Structure data | ![]() PDB-3bva: ![]() PDB-3bvb: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-2NC: ![]() ChemComp-HOH: ![]() ChemComp-NA: ![]() ChemComp-CL: ![]() ChemComp-017: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / DRUG RESISTANCE / HIV-1 / HYDROLASE-HYDROLASE INHIBITOR complex / HYDROLASE / DRUG RESISTANCE; HIV-1; D25N / MUTANT / AIDS / Aspartyl protease / Capsid maturation / Core protein / DNA integration / DNA recombination / DNA-directed DNA polymerase / Endonuclease / Lipoprotein / Magnesium / Membrane / Metal-binding / Multifunctional enzyme / Myristate / Nuclease / Nucleotidyltransferase / Nucleus / Phosphoprotein / Protease / RNA-binding / RNA-directed DNA polymerase / Transferase / Viral nucleoprotein / Virion / Zinc-finger |