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Structure paper

TitleStructural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 105, Page 2391-2396, Year 2008
Publish dateJan 29, 2008 (structure data deposition date)
AuthorsDu, Z. / Lee, J.K. / Tjhen, R. / Stroud, R.M. / James, T.L.
External linksProc. Natl. Acad. Sci. Usa / PubMed:18268334
MethodsX-ray diffraction
Resolution1.68 - 2.8 Å
Structure data

PDB-3c4b:
Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer
Method: X-RAY DIFFRACTION / Resolution: 1.68 Å

PDB-3c4t:
Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-CD:
Unknown entry

Source
  • mus musculus (house mouse)
KeywordsHYDROLASE / RNase / dsRNA binding protein / ATP-binding / Endonuclease / Helicase / Nuclease / Nucleotide-binding / Phosphoprotein / RNA-binding / RNA-mediated gene silencing

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