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TitleStructural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral Bcl-2 of Murine Gamma-Herpesvirus 68.
Journal, issue, pagesPlos Pathog., Vol. 4, Page E25-, Year 2008
Publish dateAug 24, 2005 (structure data deposition date)
AuthorsKu, B. / Woo, J. / Liang, C. / Lee, K. / Hong, H. / Xiaofeni, E. / Kim, K. / Jung, J.U. / Oh, B.
External linksPlos Pathog. / PubMed:18248095
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-2bzw:
The crystal structure of BCL-XL in complex with full-length BAD
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3bl2:
Crystal Structure of M11, the BCL-2 Homolog of Murine Gamma-herpesvirus 68, Complexed with Mouse Beclin1 (residues 106-124)
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • murid herpesvirus 4 (Murine herpesvirus 68)
KeywordsTRANSCRIPTION / APOPTOSIS / PHOSPHORYLATION / TRANSCRIPTION COMPLEX / MITOCHONDRION / TRANSMEMBRANE / VIRAL PROTEIN/APOPTOSIS / protein-protein complex / viral BCL-2 / Beclin1 / M11 / autophagy / Antiviral defense / Coiled coil / Cytoplasm / Golgi apparatus / Membrane / VIRAL PROTEIN-APOPTOSIS COMPLEX

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