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Structure paper

TitleMolecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 132, Page 259-272, Year 2008
Publish dateDec 18, 2007 (structure data deposition date)
AuthorsLaporte, S.L. / Juo, Z.S. / Vaclavikova, J. / Colf, L.A. / Qi, X. / Heller, N.M. / Keegan, A.D. / Garcia, K.C.
External linksCell(Cambridge,Mass. ) / PubMed:18243101
MethodsX-ray diffraction
Resolution2.93 - 3.02 Å
Structure data

PDB-3bpl:
Crystal structure of the IL4-IL4R-Common Gamma ternary complex
Method: X-RAY DIFFRACTION / Resolution: 2.93 Å

PDB-3bpn:
Crystal structure of the IL4-IL4R-IL13Ra ternary complex
Method: X-RAY DIFFRACTION / Resolution: 3.02 Å

PDB-3bpo:
Crystal structure of the IL13-IL4R-IL13Ra ternary complex
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCytokine/Cytokine receptor / IL4 / IL13 / receptor / cytokine / B-cell activation / Glycoprotein / Growth factor / Secreted / Immune response / Membrane / Phosphoprotein / Transmembrane / Disease mutation / Host-virus interaction / SCID / Cytokine-receptor COMPLEX / Cytokine-Cytokine receptor COMPLEX / IL13R / IL4R

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