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Structure paper

TitleFab Mor03268 Triggers Absorption Shift of a Diagnostic Dye Via Packaging in a Solvent-Shielded Fab Dimer Interface
Journal, issue, pagesJ. Mol. Biol., Vol. 377, Page 206-, Year 2008
Publish dateDec 3, 2006 (structure data deposition date)
AuthorsHillig, R.C. / Urlinger, S. / Fanghanel, J. / Brocks, B. / Haenel, C. / Stark, Y. / Sulzle, D. / Svergun, D.I. / Baesler, S. / Malawski, G. ...Hillig, R.C. / Urlinger, S. / Fanghanel, J. / Brocks, B. / Haenel, C. / Stark, Y. / Sulzle, D. / Svergun, D.I. / Baesler, S. / Malawski, G. / Moosmayer, D. / Menrad, A. / Schirner, M. / Licha, K.
External linksJ. Mol. Biol. / PubMed:18241888
MethodsX-ray diffraction
Resolution2.8 - 2.85 Å
Structure data

PDB-2jb5:
Fab fragment in complex with small molecule hapten, crystal form-1
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-2jb6:
Fab fragment in complex with small molecule hapten, crystal form-2
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

Chemicals

ChemComp-T5C:
2-{(1E,3Z,5E,7E)-7-[3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-1,3-DIHYDRO-2H-INDOL-2-YLIDENE]-4-METHYLHEPTA-1,3,5-TRIEN-1-YL}-3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-3H-INDOLIUM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / CDR / TSC / FAB / HUCAL / FLUORESCENT DYE / IMMUNOGLOBULIN DOMAIN / ANTIBODY FRAGMENT / DIAGNOSTIC IMAGING

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