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TitleStructural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5.
Journal, issue, pagesCell Death Differ., Vol. 15, Page 751-761, Year 2008
Publish dateJan 9, 2014 (structure data deposition date)
AuthorsAdams, C. / Totpal, K. / Lawrence, D. / Marsters, S. / Pitti, R. / Yee, S. / Ross, S. / Deforge, L. / Koeppen, H. / Sagolla, M. ...Adams, C. / Totpal, K. / Lawrence, D. / Marsters, S. / Pitti, R. / Yee, S. / Ross, S. / Deforge, L. / Koeppen, H. / Sagolla, M. / Compaan, D. / Lowman, H. / Hymowitz, S. / Ashkenazi, A.
External linksCell Death Differ. / PubMed:18219321
MethodsX-ray diffraction
Resolution3.2 Å
Structure data

PDB-4od2:
Crystal structure of the Fab fragment of an anti-DR5 antibody bound to DR5
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Source
  • homo sapiens (human)
KeywordsAPOPTOSIS/IMMUNE SYSTEM / IgG / Fab fragment / CRD / TNFSF / APOPTOSIS-IMMUNE SYSTEM complex

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