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Structure paper

TitleCrystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody
Journal, issue, pagesJ. Mol. Biol., Vol. 376, Page 1021-1033, Year 2008
Publish dateNov 8, 2007 (structure data deposition date)
AuthorsMichel, S. / Muller, B.H. / Bossus, M. / Ducancel, F. / Jolivet-Reynaud, C. / Stura, E.A.
External linksJ. Mol. Biol. / PubMed:18187150
MethodsX-ray diffraction
Resolution2.83 - 3.25 Å
Structure data

PDB-2zch:
Crystal structure of human prostate specific antigen complexed with an activating antibody
Method: X-RAY DIFFRACTION / Resolution: 2.83 Å

PDB-2zck:
Crystal structure of a ternary complex between PSA, a substrat-acyl intermediate and an activating antibody
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-2zcl:
Crystal structure of human prostate specific antigen complexed with an activating antibody
Method: X-RAY DIFFRACTION / Resolution: 3.25 Å

Chemicals

ChemComp-NDG:
2-acetamido-2-deoxy-alpha-D-glucopyranose

ChemComp-CL:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / human PSA / kallikrein related peptidases / antibodies / prostate cancer / Glycoprotein / Hydrolase / Polymorphism / Protease / Secreted / Serine protease / Zymogen

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