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-Structure paper
Title | Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. |
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Journal, issue, pages | Nature, Vol. 450, Page 741-744, Year 2007 |
Publish date | Sep 28, 2007 (structure data deposition date) |
Authors | Zhang, X. / Pickin, K.A. / Bose, R. / Jura, N. / Cole, P.A. / Kuriyan, J. |
External links | Nature / PubMed:18046415 |
Methods | X-ray diffraction |
Resolution | 2.9 - 3.6 Å |
Structure data | PDB-2rf9: PDB-2rfd: PDB-2rfe: |
Chemicals | ChemComp-SO4: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / kinase domain / inhibition / dimer / Alternative splicing / Anti-oncogene / ATP-binding / Cell cycle / Disease mutation / Glycoprotein / Membrane / Nucleotide-binding / Phosphorylation / Polymorphism / Receptor / Secreted / Transmembrane / Tyrosine-protein kinase / Ubl conjugation / Cytoplasm |