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Structure paper

TitleStructural implications of Siglec-5-mediated sialoglycan recognition
Journal, issue, pagesJ. Mol. Biol., Vol. 375, Page 437-447, Year 2008
Publish dateJan 17, 2008 (structure data deposition date)
AuthorsZhuravleva, M.A. / Trandem, K. / Sun, P.D.
External linksJ. Mol. Biol. / PubMed:18022638
MethodsX-ray diffraction
Resolution2.7 - 3 Å
Structure data

PDB-2zg1:
Crystal Structure of Two N-terminal Domains of Siglec-5 in Complex with 6'-Sialyllactose
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-2zg2:
Crystal Structure of Two N-terminal Domains of Native Siglec-5
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-2zg3:
Crystal Structure of Two N-terminal Domains of Native Siglec-5 in Complex with 3'-Sialyllactose
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-SIA:
N-acetyl-alpha-neuraminic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM/CARBOHYDRATE BINDING PROTEIN / Siglec-5 inhibitory receptor / two-domain structure / V-set / C2-set / Ig-like domain / sialic acid / 6'-sialyllactose complex / Cell adhesion / Glycoprotein / Immunoglobulin domain / Lectin / Membrane / Polymorphism / Transmembrane / IMMUNE SYSTEM-CARBOHYDRATE BINDING PROTEIN COMPLEX / 3'-sialyllactose complex

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