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-Structure paper
Title | Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites |
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Journal, issue, pages | Chem. Biol., Vol. 14, Page 1294-1303, Year 2007 |
Publish date | Nov 11, 2007 (structure data deposition date) |
Authors | Kaae, B.H. / Harpsoe, K. / Kastrup, J.S. / Sanz, A.C. / Pickering, D.S. / Metzler, B. / Clausen, R.P. / Gajhede, M. / Sauerberg, P. / Liljefors, T. / Madsen, U. |
External links | Chem. Biol. / PubMed:18022568 |
Methods | X-ray diffraction |
Resolution | 2.25 Å |
Structure data | PDB-3bbr: |
Chemicals | ChemComp-SO4: ChemComp-CL: ChemComp-GLU: ChemComp-BHY: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | MEMBRANE PROTEIN / AMPA RECEPTOR / GLUR2 / S1S2 / LIGAND BINDING CORE / POINT MUTATION / N775S / DIMERIC POSITIVE MODULATOR / AGONIST / Cell junction / Glycoprotein / Ion transport / Ionic channel / Lipoprotein / Membrane / Palmitate / Phosphorylation / Postsynaptic cell membrane / RNA editing / Synapse / Transmembrane / Transport |