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TitleStructure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor
Journal, issue, pagesGenes Dev., Vol. 21, Page 2711-2716, Year 2007
Publish dateSep 7, 2007 (structure data deposition date)
AuthorsLiu, X. / Marmorstein, R.
External linksGenes Dev. / PubMed:17974914
MethodsX-ray diffraction
Resolution1.671 Å
Structure data

PDB-2r7g:
Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain
Method: X-RAY DIFFRACTION / Resolution: 1.671 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • human adenovirus 5
KeywordsTRANSCRIPTION REPRESSOR / CELL CYCLE / Retinoblastoma protein / E1A / E2F displacement

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