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Structure paper

TitleStructure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense.
Journal, issue, pagesScience, Vol. 317, Page 1552-1554, Year 2007
Publish dateJul 26, 2007 (structure data deposition date)
AuthorsHadders, M.A. / Beringer, D.X. / Gros, P.
External linksScience / PubMed:17872444
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-2qqh:
Structure of C8a-MACPF reveals mechanism of membrane attack in complement immune defense
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NI:
NICKEL (II) ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / MEMBRANE PROTEIN / MACPF / MEMBRANE PERFORATION / Cleavage on pair of basic residues / Complement alternate pathway / Complement pathway / Cytolysis / EGF-like domain / Glycoprotein / Immune response / Innate immunity / Membrane attack complex / Polymorphism / Secreted

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