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TitleRelease of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 14, Page 814-823, Year 2007
Publish dateMay 17, 2007 (structure data deposition date)
AuthorsMitin, N. / Betts, L. / Yohe, M.E. / Der, C.J. / Sondek, J. / Rossman, K.L.
External linksNat. Struct. Mol. Biol. / PubMed:17704816
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-2pz1:
Crystal Structure of Auto-inhibited Asef
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Helical Bundle / Beta Barrel / Beta Sandwich

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