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Structure paper

TitleAn unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 104, Page 12737-12742, Year 2007
Publish dateJun 7, 2007 (structure data deposition date)
AuthorsHuyton, T. / Zhang, J.G. / Luo, C.S. / Lou, M.Z. / Hilton, D.J. / Nicola, N.A. / Garrett, T.P.
External linksProc. Natl. Acad. Sci. USA / PubMed:17652170
MethodsX-ray diffraction
Resolution4 Å
Structure data

PDB-2q7n:
Crystal structure of Leukemia inhibitory factor in complex with LIF receptor (domains 1-5)
Method: X-RAY DIFFRACTION / Resolution: 4 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsCYTOKINE receptor/CYTOKINE / CYTOKINE CELL SURFACE RECEPTOR COMPLEX LIFR LIF / CYTOKINE receptor-CYTOKINE COMPLEX

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