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| Title | Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry |
|---|---|
| Journal, issue, pages | Protein Eng. Des. Sel., Vol. 20, Page 397-403, Year 2007 |
| Publish date | Mar 15, 2007 (structure data deposition date) |
Authors | Sami, M. / Rizkallah, P.J. / Dunn, S. / Molloy, P. / Moysey, R. / Vuidepot, A. / Baston, E. / Todorov, P. / Yi, L. / Gao, F. ...Sami, M. / Rizkallah, P.J. / Dunn, S. / Molloy, P. / Moysey, R. / Vuidepot, A. / Baston, E. / Todorov, P. / Yi, L. / Gao, F. / Boulter, J.M. / Jakobsen, B.K. |
External links | Protein Eng. Des. Sel. / PubMed:17644531 |
| Methods | X-ray diffraction |
| Resolution | 1.89 - 2.3 Å |
| Structure data | ![]() PDB-2p5e: ![]() PDB-2p5w: ![]() PDB-2pye: ![]() PDB-2pyf: |
| Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-MG: ![]() ChemComp-SO4: ![]() ChemComp-IPA: ![]() ChemComp-EPE: ![]() ChemComp-HOH: ![]() ChemComp-CA: ![]() ChemComp-PGE: ![]() ChemComp-7PE: ![]() ChemComp-PG4: |
| Source |
|
Keywords | IMMUNE SYSTEM / T-CELL RECEPTOR / CDR3 / PHAGE DISPLAY / MUTANT / HIGH AFFINITY / NY-ESO-1 / CDR2 |
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homo sapiens (human)
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